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The effects of SSRIs on mortality in young rats may be mediated by SSRI-induced placental insufficiency rather than direct toxic effects on neonatal development and mortality ( p = 0.001) and CYP1A1 ( p = 0.002) were still observed between the study groups, although there was no significant effect on placental GST activity

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While direct clinical trials specifically on active acne vulgaris are limited, the observed benefits are highly relevant to acne-prone skin: Improved Skin Density and Thickness: Clinical studies have shown GHK-Cus ability to increase skin density and thickness, which can contribute to a plumper appearance and potentially reduce the visibility of shallow scars