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The conserved mechanisms of the SSP, including redox homeostasis, one-carbon metabolism, and drug resistance regulation, can serve as common targets for cross-cancer therapeutic interventions

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The induction of stress by therapy could affect tumor cells in different ways: including the induction of autophagy, cellular senescence, apoptosis, or necrosis, all of which are, in part, interconnected, and damages induced by therapyeither chemo- or radiotherapy could induce autophagy as a housekeeping process (Kanzawa et al., 2012)

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EFSA J 12(5):3660 Leung AM, Avram AM, Brenner AV, Duntas LH, Ehrenkranz J, Hennessey JV et al (2015) Potential risks of excess iodine ingestion and exposure: statement by the american thyroid association public health committee