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Furthermore, many GDPs such as 3,4-dideoxyglucosone-3-ene (3,4-DGE) are reactive carbonyl compounds which along with glucose form advanced glycation end-products (AGEs), binds to free amino groups on membrane proteins or lipids contributing to pathophysiological alterations in the peritoneal membrane (Linden et al., 2002

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Treatment with nicotinamide and EGCG restored GTP and improved cleanup markers

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