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Elucidating these mechanisms may explain what determines the specificity of BDNF vesicle fusion at synaptic versus extrasynaptic sites

In this line, a direct role for GPX4 in the process of macrophage polarization has been suggested

This lactate is then transported via MCTs to the extracellular space, where neurons uptake it through MCTs, converting it to pyruvate and acetyl-CoA for ATP production via OXPHOS, which supports synaptic formation and neurotransmitter release [7, 15]

2017;12:e0176887

doi: 10.3390/molecules26113421 172

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