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Description

A higher concentration of plasma 5HT, which was stored in platelets, may reflect an elevated activity of the 5HT transporter, and, as a result, greater sensitivity to SSRIs in those patients

Plasma samples from 136 participants with MDD enrolled into the Mayo Pharmacogenomics Research Network Antidepressant Medication Pharmacogenomic Study (PGRN-AMPS) were profiled at baseline and after 8 weeks of treatment