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Spinal cord injury was induced in male Albino Wistar rats by controlled pressure (a vascular clip Aesulap 0.10-0.15 N) on the exposed spinal cord (at the level of Th12) for 30 seconds

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Involved in the synthesis of neurotransmitters, SAM may be implicated in mood disorders

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NNMT inhibitors and standards for LC/MS/MS studies were purchased from established commercial suppliers or synthesized in-house by established synthetic schemes as described previously