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A prime example is acetaminophen (APAP) overdose: The reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI) depletes intracellular glutathione (GSH), tipping the redox balance toward uncontrolled oxidative stress

All the authors participated in drafting, revising, and critically reviewing the manuscript and approved the final version for publication

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These results were comparable to that of olanzapine treatment in ketamine-treated animals, which represents that hesperidin and CoQ10 might follow the same mechanism of action as olanzapine