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Lipopolysaccharide induces CD38 expression and solubilization in J774 macrophage cells

Pain 1977;4:16174.ArticlePubMed 8

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When you are fighting off harmful bacteria, virus or other germs, our body produces more of these immune cells this causes the swelling

Importantly, however, the observed protective effect of higher IGF-1 was observed upon adjustment of BMI, suggesting that it is not fully mediated by BMI as marker for fat mass