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This can manifest as fatigue, mood swings, or reproductive challenges

For the wash-out experiments cells were similarly handled but washed three times with Opti-MEM + 1% FBS (100 l) before adding 100 l fresh media with 6 ng/ml PMA solution without any inhibitor for 6 h (Wash-out)

J Park Dis (2018) 8(s1):S11521

Future investigations on how the biological clock governs cell proliferation and growth and on the potential implications for the onset of human diseases are warranted