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The best choice depends on your specific situation, lab values, and health status

We usually tell the parent to look for changes after approximately 4 doses, (= ~2 weeks)

In Heffernan et al

Post-weight-loss patients undergoing body contouring surgery (particularly longer procedures such as a body lift (belt lipectomy) or combined abdominoplasty (tummy tuck) and thighplasty (thigh lift)) sit at the higher end of the risk spectrum for several reasons (4, 9), and B12 deficiency is one contributor

Individual Variation in Dose Response Metabolic differences, such as variations in sex hormone-binding globulin levels or differences in aromatase activity, often mean that what works for one patient may be suboptimal for another