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Glucose metabolism impairment is involved in the pathogenesis of PD Diabetes mellitus (DM) and PD share some pathophysiological mechanisms, such as oxidative stress, mitochondrial dysfunction, neuroinflammation, insulin resistance, and protein misfolding [59]

For more on the delivery system, see All About Liposomes

Thus, ferritin abundance controls ferroptosis sensitivity: ferritin raises the susceptibility to ferroptosis when unstable iron pools are limited because it promotes iron ion preservation

The residue was purified by flash silica gel column chromatography (10% EtOAc in hexanes) to afford the title compound

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