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For example, hawthorn fruit polysaccharides alleviate NAFLD in mice by improving gut flora dysbiosis (affecting Lachnospiraceae and Dubosiella ), increasing intestinal acetate levels, and subsequently correcting hepatic amino acid, lipid, and vitamin metabolic disorders

However, no combination studies have been conducted, and the interaction between telomerase activation and sirtuin-mediated pathways is complex -- SIRT1, for example, can influence telomere biology through effects on shelterin complex proteins

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Regulation of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 cells by 2-hydroxy-3-en-anhydroicaritin involves down-regulation of NF-kappaB and MAPK expression

doi: 10.1016/j.jff.2015.11.007 154 SilaA.SayariN.BaltiR.Martinez-AlvarezO.Nedjar-ArroumeN.MoncefN.et al