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Homocysteine level is a more direct measure of the function of vitamin B12 and folic acid (compared to red blood cell or serum testing)

Much of our understanding comes from laboratory research, animal studies, and growing clinical experience

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Some of this excess can be stored (some 25 mg), meaning that deficiency symptoms may not occur until 35 years after the diet fails to provide sufficient vitamin B12 or its absorption becomes inadequate [3]

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