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Taken together, mHtt can impede the dynamic alterations of mitophagy, mitochondrial biogenesis, and mitochondrial fission/fusion, resulting in the disruption of mitochondrial structure and function

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Carotenoids react with LOO at conjugated double bonds, producing a radical adduct (LOO-CAR ) that undergoes resonance stabilization at low oxygen pressure, favouring the chain-termination reaction over the chain-propagation reaction [151]