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Dosing began at 0.25 mg of each active drug and escalated every four weeks until the full 2.4 mg dose was reached by week 16

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Typical protocol structure: Dose: 100-200mcg based on individual response Frequency: 3-5 times per week Timing: 1-3 hours before bed (experiment to find your optimal window) Cycle length: 4-8 weeks Break period: 2-4 weeks between cycles The frequency debate generates significant discussion

The FDA panel will vote on additional compounds on Friday

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Unknown factors include potential hormonal effects, cellular signaling imbalance, and unintended tissue growth responses after prolonged exposure