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For example, in colorectal cancer, p53 non-transcriptionally inhibits dipeptidyl peptidase 4 activity to prevent Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-mediated lipid peroxidation and erastin-induced ferroptosis, whereas TP53 deficiency enhances this process [46,47]

Part 3: Orally active anti-inflammatory agents

405 Other immune cells Experimental evidence indicates that mice lacking MyD88, a critical adapter molecule for TLR signaling, lack ABCs and that pharmacological inhibition of this signaling axis effectively impedes the commitment of B cells to the ABC lineage

doi: 10.1016/j.bbapap.2017.07.003 251 XuZJinXCaiWZhouMShaoPYangZet al

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doi: 10.1203/01.PDR.0000090926.16166.3F