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The lowest level of antioxidant intake or tissue concentration results in nutrient deficiency if the antioxidant is essential (vitamins and minerals)

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doi: 10.3389/fmicb.2023.1207132 184

By contrast, knockout mice for ANGPTL6 show an increased incidence of obesity, insulin resistance, and increased fat content in peripheral organs (especially the liver and skeletal muscle) ( In both humans and mice, fastinginduced adipose factor (FIAF) is another very important hepatokine

The flipping of PS to the cytosolic leaflet of trans-Golgi has been shown to be due to Arl1 activation of the flippase Drs2 in the trans-Golgi network, and has recently been reviewed 71