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The current review summarizes the most current examples of leishmanicidal agents based on 4-aminoquinolines focusing the analysis on two essential aspects: (i) structureproperty relationship to identify the key pharmacophores and (ii) mode of action focused on key targets in parasite survival ( e.g

Glutathione Chen J., et al

The dye is essentially non-toxic and once bound to DNA produces a stable fluorescent signal for up to 72 hours

Childs JM, Sperling LC (2013) Histopathology of scarring and nonscarring hair loss

Two-bottle choice (2BC) The standard 2BC paradigm was as previous reported [25]

In the second step, the homodimeric enzyme GS, a member of the ATP-grasp superfamily, rapidly catalyzes the binding of -glutamylcysteine with glycine, obtaining GSH (8, 9)