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Lastly, to further identify the exact site in the ETC modulating response to ferroptosis in N1IC cells we also inhibited complex III, the other major site of ROS production in the mitochondria, with antimycin and did not find any difference in RSL3 sensitivity (Fig

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Aging ECs are typically morphology flat and enlarged, increased polyploidy, decreased NO bioavailability, and secretion of multiple pro-inflammatory cytokines (Hwang et al., 2022)

La carnitina facilita questo processo accelerando il trasporto degli acidi grassi nei mitocondri, dove vengono trasformati in ATP ( adenosina trifosfato ), la moneta energetica delle cellule