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Moreover, the association between glutamatergic metabolites and clinical symptoms did not significantly change over the two years (PANSS score*time insignificant) (Table 3)

Another critical mechanism by which oxidative stress contributes to ethanol-induced depression involves the dysregulation of neurotransmitter systems

Increased mIns/Cr, [mIns + Gly]/Cr and Gly/Cr ratios were found in all grades of glial tumours compared with normal-appearing white matter [79]

This region-specific action is associated with its local stimulation of hormone-sensitive lipase and enhanced fatty acid oxidation, suggesting potential for site-selective metabolic modulation without systemic hormonal changes

doi: 10.1007/s13205-020-02312-3 70 WangW.LiX.ZhuJ.LiangZ.LiuF.SunX.et al

Al-Aly, Z., Maddukuri, G