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Final samples pooled libraries were sequenced on ILLUMINA Miseq with 2*150 micro cartridge (2 4 million of 150-base reads), corresponding to 2 300,000 reads per sample after demultiplexing

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Treatment with curcumin has been shown to increase the number of follicles at different developmental stages and in GCs, improve histological appearance of oocytes, and markedly reduce atretic follicles, lipid peroxidation, hemorrhage around the corpus luteum, and vascular congestion in the ovarian stroma (Alekseyeva et al., 2011