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With increasing concentrations of compound 40 , we observed an increase in a peak around 100 kDa, corresponding in size to the full-length TRF1 dimer (Fig

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1 Supporting Data The approval for dato-DXd was supported by findings from 2 clinical trials: the Efficacy was evaluated in a pooled subgroup analysis of the TROPION-Lung05 and TROPION-Lung01 trials composed of 114 patients with locally advanced/metastatic EGFR -mutated NSCLC who had received prior EGFR-directed therapy and platinum-based chemotherapy

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