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66 , e2200248 (2022)

[255-258] We conclude that NO (nitric oxide) plays a critical immunoregulatory role and NO modulation may prevent the onset of autoimmune reactions[259] Research has shown that IL-17 and the TH-17 system activates iNOS and initiates tissue destruction in autoimmunity: Interleukin-17 is a proinflammatory cytokine involved in autoimmune disorders