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Statements Data availability statement The data presented in the study are deposited in the National Center for BiotechnologyInformation (NCBI) Sequence Read Archive (SRA) repository, accession number PRJNA1298771

Stay away from incompatible substances such as strong oxidants.

Another circadian clock protein PER2 inhibits the expression of PAI-1 in a CLOCK/BMAL1-dependent manner as an important factor in the development of these metabolic diseases after the circadian clock system is dysregulated (Oishi et al., 2009)