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A trend towards higher FXIa levels in the mTICI: 3 group (n = 60), (2.7% [0.96.2]) than mTICI: 02b group (n = 15), (1.4% [0.67.5]) and mTICI: 2c group (n = 15),(1% [0.32.6]) (H(2) = 4.7, p = 0.09) was observed

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Furthermore, evidence points toward exposure between birth and approximately 5 years of age as the period of highest risk, with the risk during prenatal exposure being significant in numerous studies [4] albeit less consequential [2,3]

Computational models suggested that the presence of Frag 176-191 may alter the predicted binding dynamics of chemo-related intervention agents to these targets, most notably by reducing the estimated mitigation constant of doxorubicin for the progesterone receptor

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