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We recruited all patients with either PWID or MSM, or both whereas patients with neither PWID nor MSM were randomly recruited

Blocking downstream sensing pathways Despite a reduction in mtDNA release, residual cytosolic or extracellular mtDNA can activate innate immune receptors to sustain inflammation

Side chains of Ala920 on EGFR and +1 pTyr on the peptide substrate as shown in spacefill representation

[DOI] [PubMed] [Google Scholar] 53.Franceschi C, Campisi J

CBS inhibitors To obtain more efficient and selective CBS inhibitors, an enzyme activity assay method compatible with high-throughput screening is needed