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The results showed that probiotic/prebiotic supplementation had no significant direct effect on TSH, free thyroxine and free triiodothyronine levels but significantly reduced thyrotrophin receptor antibody levels, revealing the potential value of probiotics and prebiotics in regulating autoimmune responses (Sanders et al., 2019)

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Representative domains include: Gastrointestinal and hepatic models: Protection against ulcers, leaky gut, IBSlike symptoms, Crohntype inflammation, and toxic liver injury (e.g., CCl4, NSAID, and alcohol models), with improved mucosal healing and barrier integrity

Avoid repeated freeze-thaw cycles, protect from light, and use bacteriostatic water rather than sterile water for reconstitution to prevent microbial contamination during multi-dose use