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discard if cloudy or particulate Dosing Calculation Example: If reconstituting 5 mg with 2.5 mL bacteriostatic water, the concentration is 2 mg/mL (2000 mcg/mL)

2 Differential diagnoses include linear immunoglobulin A dermatosis, pemphigus, acute generalized exanthematous pustulosis, and staphylococcal scalded skin syndrome

Additionally, it is subject to limited absorption by the small intestine and fast elimination by the gallbladder and its oral bioavailability is minimal

Sakuragi, M

Jacobson T, Maki K, Orringer C, Jones P, Kris-Etherton P, Sikand G, Forge R, Daniels S, Wilson D, Morris P, Wild R, Grundy S, Daviglus M, Ferdinand K, Vijay K, Deedwania P, Aberg J, Liao K, McKenney J, Ross J, Braun L, Ito M, Bolick J, Dicklin M, Kirkpatrick C, Rhodes K, Smith N, Blackett P, DeFerranti S, Gidding S, Davey R-E, McCrindle B, McNeal C, Urbina E, Dayspring T, Underberg J, Lopez J, Pirzada A, Roderguez C, Fichtenbaum C, Gallant J, Horberg M, Longenecker C, Myerson M, Overton E, Coblyn J, Curtis J, Plutzky J, Solomon D, Bays H, Brown W

Product glucuronides are exported from hepatocytes by MRP2 (canalicular, into bile) and MRP3/MRP4 (basolateral, into blood for renal excretion)