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doi: 10.1016/S0140-6736(94)92211-X

4 Interplay between mitochondrial dysfunction and fatty acid metabolic disturbances in the failing heart Mitochondrial dysfunction and FAO disorders reinforce each other in the failing heart: ETC defects and m loss suppress FAO, while dysregulated FAO promotes oxidative stress, lipotoxicity, and structural damage, further compromising mitochondrial function

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In most 2026 research models, a mandatory rest period of at least 2 to 4 weeks is recommended after a 4-week cycle

faecalis , FeCl 3 concentrations above 0.5 mM do not lead to further significant increases in intracellular iron levels (21)