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This is important in tissues that rely heavily on fat as a fuel source, like skeletal muscle and the heart

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When sleep onset was detected in a sleep-deprived rat, the disc was slowly rotated at a moderate speed of 3.5 rpm by a computerized monitoring system, forcing both rats to remain awake and walk against the direction of disc rotation to avoid being forced into the water

The interplay between NF-B and Nrf2 pathways is crucial in managing OS and inflammation, as seen in the effects of dietary phytochemicals that can activate these defense systems (Wu et al., 2022)

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