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In: "Mesenchymal Stromal Cells: Biology and Clinical Applications"

Some of the most important ones for weight regulation include: GLP-1 (glucagon-like peptide-1): Released from the gut after eating, it signals fullness, slows digestion, and regulates blood sugar

But their translation into routine practice necessitates rigorous evaluation of safety, durability of efficacy, and patient heterogeneity-factors that remain insufficiently addressed to date ( 4.1 Liver-selective THR agonists for metabolic and fibrotic correction Emerging pharmacological strategies have increasingly targeted THR signaling, particularly in the treatment of NASH and progressive MAFLD (158, 159)