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These mechanisms are relevant to both aging biology and cancer biology, which is why the topic appears in scientific discussions

Neuroplasticity driven by HGF/c-Met signaling includes upregulation of brain-derived neurotrophic factor (BDNF), activation of postsynaptic density protein-95 (PSD-95), and increased expression of GluN2B-containing NMDA receptors

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Blood Press Monit 9:3137 DElia L, la Fata E, Galletti F, Scalfi L, Strazzullo P (2017) Coffee consumption and risk of hypertension: a doseresponse meta-analysis of prospective studies