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A protein-protein interaction (PPI) network was constructed, revealing 16 genes with significantly altered expression levels (Fig

However, the researchers found that intracellular lipoxygenase levels were significantly increased

ROS (such as superoxide anion, hydrogen peroxide, and hydroxyl radicals) are produced by activated immune cells as part of the respiratory burst that kills pathogens [16]

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Puerarin suppresses macrophage M1 polarization to alleviate renal inflammatory injury through antagonizing TLR4/MyD88-mediated NF-B p65 and JNK/FoxO1 activation