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[13] [15] Other rare adverse effects include dizziness, headache, and fatigue

Via similar logic, interventions in individuals who do not yet exhibit age-related cognitive impairment (either dementia or mild cognitive impairment) may also yield no effects of B vitamins/homocysteine lowering as it is difficult to prevent something that is not happening (55)

NAD+ shortage especially affects muscle stem cells, where mitochondrial problems signal stem cell aging, which results in fewer stem cells and less regenerative potential

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Unlike oral supplements, B12 injections bypass the digestive system and are absorbed directly into the bloodstream, ensuring maximum effectiveness