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6 Discussion Synthesizing the foregoing evidence, this article proposes a central hypothesis of ferroptosis in periodontitis: ferroptosis is not merely a passive accompaniment to disease progression, but has the potential to evolve into an important node and signal amplification link within the pathological network

The alteration method involves a coating of the surface with a biological bonding agent, non-ionic surfactant and specific cell or antibodies or by albumin protein

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Bayona-Bafaluy, M

10.1161/CIRCRESAHA.113.301241 201

Likewise, methods used to assess mtDNA mutations and deletionsincluding long-range PCR, NGS, and targeted mitochondrial arraysvary widely in their ability to detect low heteroplasmy or large structural variants (131133)