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doi: 10.1016/j.canlet.2015.07.031 71 OgiharaKKikuchiEOkazakiSHagiwaraMTakedaTMatsumotoKet al

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Moreover, overexpression of genes such as glutathione reductase 1 (GSR1) and glyoxalase enzyme 1 (GLO1) has been strongly correlated with anxiety phenotypes (Hovatta et al., 2005), with GLO1 inhibitors showing potential in alleviating anxiety (Distler et al., 2012)

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Some, however, including certain birds, guinea pigs, bats, primates, and humans, lack the necessary biosynthetic apparatus and must acquire vitamin C through external sources, i.e., diet