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In humans, various isoforms of GST are present in virtually all tissues with the liver exhibiting the highest cytosolic GST activity level followed by kidney, lung, and intestine (Pacifici et al., 1988)

PRP provides a concentrated source of growth factors and cytokines that stimulate cell proliferation and tissue repair

Collectively, these studies suggest MPs/NPs potentially exhibiting neurotoxic effects on cerebral tissue and vascular integrity, while negative effects during fetal exposure may be mitigated by placental adaptation

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Beyond their engineering advances, OoC systems are increasingly recognized for their potential to bring preclinical research closer to clinical reality, especially when incorporating patient-derived cells

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