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AMT lacks receptor specificity, which increases the off-target distribution 118,119

PangBDongGPangTSunXLiuXNieYet alAdvances in pathogenesis and treatment of vascular endothelial injury-related diseases mediated by mitochondrial abnormality

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NPs allow precise delivery of the CRISPR/Cas9 components to neurons, allowing for accurate gene editing and potential disease modification (153)

Because sulfoxide metabolites are more potent nephrotoxicants than their parent S -conjugates, more research is needed on the extent of formation of S -(1,2-dichlorovinyl)-L-cysteine and N -acetyl- S -(1,2-dichlorovinyl)-L-cysteine sulfoxides by human tissues (liver and kidney), the extent to which these reactions occur in vivo, the enzymes involved, and their interindividual variability, including the role of genetic polymorphisms

From Krebs to clinic: glutamine metabolism to cancer therapy