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The proposed mechanism includes a peptide-induced support of -AR gene transcription, potentially leading to increased mRNA expression and receptor density on adipocyte membranes

16 Another recent retrospective study found that if those with pre-existing avascular necrosis and subchondral insufficiency fracture are excluded from analysis, patients treated with hip CSI did not have significantly higher rates of short-term hip OA progression or femoral head articular surface collapse

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However, collagen supplements are most effective when combined with a nutritious diet, sun protection, and a consistent skincare routine

doi: 10.1016/S0735-1097(02)01797-7

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