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Patel Aanal

Wen L, Bi D, Shen Y (2024) Complement-mediated synapse loss in Alzheimers disease: mechanisms and involvement of risk factors

In various embodiments, the first lipid-containing conjugation partner is a compound of the formula (IIA-1): the amino acid-comprising conjugation partner comprises a structure of the the conjugate is a compound of the formula (IC): wherein Ra, Rb, Rc, L1, L2, Z1, Z2, R1, R2, Rx, Ry, R3, R4, R5, R6, R7, R8, R9, A1, k, v, and n are as defined in the compound of formula (I) or any embodiment thereof

Actin dynamics

The average optical volume of cells significantly increased (Figure 5A)

If one reduces Kupffer cell activation to protect the liver, could that compromise systemic pathogen clearance