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A comprehensive review in Nature Reviews Disease Primers described B12 deficiency as a significant and underrecognized public health concern, particularly among older adults, individuals with gastrointestinal conditions, and those following plant-based diets (Green et al., Nat Rev Dis Primers , 2017)

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Gut Health: Given its origin, it's no surprise that a massive body of research centers on its protective effects on the gastrointestinal tract, from the esophagus to the colon

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1,000 units/20 g) 6 and 18 h after CLP increases the survival rate of mice by 40% (128)

Fox says that if your pet has a demonstrated medical need for supplementation, correcting vitamin B12 levels can: Improve appetite Address certain gastrointestinal issues Allow for necessary weight gain Improve metabolic abnormalities (if present) Vitamin B12 Deficiency in Dogs Vitamin B12 deficiency in dogs is something a veterinarian can only diagnose through lab work and physical assessment