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Therefore, if a single microbes metabolism changes, such as in antimicrobial resistance, then Raman spectroscopy can be used to detect the deviation from the baseline fingerprint

Deshwal, S., Forkink, M., Hu, C

E .coli cells can be lysed by French press (though this method is not readily scalable), sonication or detergent-based lysis (many commercial lysis reagents are available)

Leonarduzzi G., Sevanian A., Sottero B., Arkan M

Co-expression of basic helixloophelix protein (bHLH) and transcriptional activator-Myb genes induced anthocyanin biosynthesis in hairy root culture of Nicotiana tabacum L and Ipomea tricolor

(Although multiple sclerosis (MS) is classically an autoimmune inflammatory demyelinating disease rather than a primary proteinopathy, we include it here due to overlapping chronic CNS injury and immune dysregulation influenced by the microbiome.) For each disease, specific microbial taxa, metabolites, and pathways implicated in pathogenesis are discussed