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Oral administration of SA (10, 30, and 100 mg/kg) to female Balb/c mice post-TNBS instillation significantly improved colonic weight and length, reduced macroscopic and microscopic colonic changes, and lowered myeloperoxidase activity, malondialdehyde levels, and tumor necrosis factor-alpha expression compared to TNBS control [389]

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Research also suggests that this compound supports neuronal health through modulation of the caspase-3 enzyme system , a key initiator of apoptosis [1] [2]

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Pharmacotherapy 29 , 10891102 (2009)

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