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The largest Phase 2b trial (502 participants, 24 weeks) did not show statistically significant weight loss versus placebo

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL NDC 70771-1688-1 Cyanocobalamin Injection, USP 1,000 mcg/mL FOR IM OR SC USE ONLY 1 mL Multiple-dose Vial Rx only NDC 70771-1668-7 Cyanocobalamin Injection, USP 1,000 mcg/mL FOR INTRAMUSCULAR OR SUBCUTANEOUS USE ONLY 25 X 1 mL Multiple-dose Vials Rx only NDC 70771-1689-1 Cyanocobalamin Injection, USP 10,000 mcg/10 mL (1,000 mcg/mL) FOR INTRAMUSCULAR OR SUBCUTANEOUS USE ONLY Contains Benzyl Alcohol as a Preservative

However, substantial heterogeneity among studies was observed, likely attributable to differences in dosage, baseline B12 status, and population characteristics

Supports energy efficiency and mitochondrial function

ICH Q5C: Quality of biotechnological productsstability testing of biotechnological/biological products

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