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It is hard to reduce the total body load if one is continually exposed to the toxin

113 , E7564E7571 (2016)

The biosynthesis pathway the upstream production of fresh GSH is the topic of a later article in this cluster

While targeting GPX4 holds promise in cancer treatment, a challenge arises from its widespread expression in both cancer and immune cells, which can potentially cause side effects when using traditional GPX4 inhibitors