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doi: 10.1161/STROKEAHA.107.493593 77 BugnicourtJMGodefroyOChillonJMChoukrounGMassyZA

NAD+ therapy is generally safe and well-tolerated, supporting cellular metabolism, energy production, and overall health

Dosing is oral, typically taken in the morning with or without food, and the 24-hour half-life makes once-daily administration pharmacokinetically appropriate

In Phase I results , adults taking the drug lost about 8% to 10% of their body weight over 12 to 13 weeks

Any use outside a research setting carries risks, and dosing recommendations are speculative based on anecdotal and preclinical data

It's experienced a minor stability insult that reduced potency by perhaps 35%