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259,260 Metabolic reprogramming toward glycolysis in GSCs facilitates epigenetic reprogramming of GBM cells and immune evasion by promoting lactate-derived histone Kla and the subsequent transcriptional upregulation of CD47

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While these benefits are promising, be aware that you might experience mild stomach discomfort

Isolation of WAT stromal vascular cells and adipocyte differentiation To isolate the stromal vascular fraction, minced iWAT (combined depots from 45 mice per genotype) from 46-week-old mice was digested in 1 mg ml 1 collagenase D (Roche) with 1.5% BSA in sterile Hanks Balanced Salt Solution and incubated in a 37 C shaking water bath for 1 h

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