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Understanding these side effects and how to manage them is crucial for anyone considering glutathione supplementation

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Accumulating evidence further demonstrates that in pSS models, reduced gut microbiome diversity and diminished production of microbiota-derived metabolites lead to decreased tolerogenic dendritic cells (DCs) and Th17/Treg imbalance, consequently promoting autoantibody accumulation and exacerbation of glandular inflammatory responses in pSS (203)

Therefore, significant inter-individual variation in clearance may exist for any toxicant found to be a substrate of GST

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