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Four arguments support this position: (1) HHV-6 can cause demyelinative CNS degeneration and active HHV-6 infections are associated with other demyelinating diseases of the CNS

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GR knockout seemed to affect these pathways particularly, hinting at a metabolic recalibration in response to the redox imbalance

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The rat knee OA model was established using the modified Hulth method (Hulth group and pioglitazone group) [25]

Research to date, particularly in AMS and related hypoxic conditions, indicates that TCM and TM interventions, mainly through herbal medicines, may exert beneficial effects on HACE by regulating inflammatory responses, reducing oxidative stress, improving cerebral blood flow and microcirculation, providing neuroprotection, and potentially affecting cell metabolism (Wang et al., 2023)