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Moreover, inhibition of mGluR5 was shown to enhance the potency of chemotherapeutic agents in hepatocellular carcinoma cell lines and attenuate chemotoxicity over DNA damage by downregulating Ca 2+ -dependent MAPK signaling in the normal liver (76)

The tissues were fixed in 4% paraformaldehyde and then embedded in paraffin

Biotin A vitamin known to promote visibly thicker, healthy-looking hair

More importantly, this pro-inflammatory oxidative environment alters astrocytic physiological states, potentially impairing their ability to form TNTs or generate EVs, thereby directly inhibiting mitochondrial transfer mechanisms